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Application of Various Delivery Methods for CRISPR/dCas9.
Molecular Biotechnology ( IF 2.6 ) Pub Date : 2020-06-24 , DOI: 10.1007/s12033-020-00258-8
Zhixi Liu 1, 2, 3 , Zhi Liao 4 , Yan Chen 1 , Lizhu Han 2, 3 , Qinan Yin 2, 3 , Hongtao Xiao 1, 2, 3
Affiliation  

As gene-editing technology has become more and more popular in the life sciences, CRISPR has brought good news to scientific researchers because of its efficiency, convenience, and wide application. Its wide application has also promoted the development of basic scientific research, agriculture, basic medicine, and clinical treatment. However, how the CRISPR/dCas9 system is effectively delivered to the target organs or cells is still unknown. This paper briefly introduces the CRISPR/dCas9 system and then lists some common delivery methods and their characteristics.



中文翻译:

CRISPR / dCas9各种递送方法的应用。

随着基因编辑技术在生命科学中越来越流行,CRISPR因其高效,便捷和广泛应用而给科研人员带来了好消息。它的广泛应用也促进了基础科学研究,农业,基础医学和临床治疗的发展。然而,如何将CRISPR / dCas9系统有效地传递至靶器官或细胞仍是未知的。本文简要介绍了CRISPR / dCas9系统,然后列出了一些常见的递送方法及其特征。

更新日期:2020-06-24
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