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Broadening primate genomics: new insights into the ecology and evolution of primate gene regulation.
Current Opinion in Genetics & Development ( IF 4 ) Pub Date : 2020-06-20 , DOI: 10.1016/j.gde.2020.05.009
Jordan A Anderson 1 , Tauras P Vilgalys 2 , Jenny Tung 3
Affiliation  

Comparative analyses have played a key role in understanding how gene regulatory evolution contributes to primate phenotypic diversity. Recently, these studies have expanded to include a wider range of species, within-population as well as interspecific analyses, and research on wild as well as captive individuals. This expansion provides context for understanding genetic and environmental effects on gene regulation in humans, including the importance of the pathogen and social environments. Although taxonomic representation remains biased, inclusion of more species has also begun to reveal the evolutionary processes that explain whether and when gene regulation is conserved. Together, this work highlights how studies in other primates contribute to understanding evolution in our own lineage, and we conclude by identifying promising avenues for future work.

中文翻译:

扩大灵长类基因组学:对灵长类基因调控生态和进化的新见解。

比较分析在理解基因调控进化如何促进灵长类动物表型多样性方面发挥了关键作用。最近,这些研究已经扩展到包括更广泛的物种、种群内和种间分析,以及对野生和圈养个体的研究。这种扩展为理解基因和环境对人类基因调控的影响提供了背景,包括病原体和社会环境的重要性。尽管分类学表示仍然存在偏见,但纳入更多物种也开始揭示解释基因调控是否以及何时保守的进化过程。总之,这项工作突出了对其他灵长类动物的研究如何有助于理解我们自己谱系的进化,
更新日期:2020-06-19
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