Fusarium wilt is the most destructive fungal disease in flax, limiting flax cultivation in all the main flax and linseed growing countries. The causative agent is seedborne and soilborne fungus F. oxysporum f. sp. lini. Here, we report, for the first time, genome assemblies of five highly pathogenic isolates of Fusarium oxysporum f. sp. lini, namely monoisolate 39 and strains F329, F324, F282, F287. In addition, syntenic analysis provided a powerful approach to distinguish between core and lineage-specific parts of the genome. These results lay a solid foundation for comparative genomics studies of plant fungal pathogens, evolution of pathogenicity, and virulence factors underlying the dynamics of host-pathogen interactions, thus eventually offering solutions to Fusarium disease control.

镰刀菌枯萎病是亚麻中最具破坏性的真菌病，限制了所有主要亚麻和亚麻籽生长国家的亚麻种植。病原体是种子传播的和土壤传播的真菌F. oxysporum f。sp。莉妮。在这里，我们首次报告了尖孢镰刀菌f的五个高致病性分离株的基因组组装。sp。莉妮，即单分离株39和菌株F329，F324，F282，F287。此外，同步分析提供了一种强有力的方法来区分基因组的核心部分和谱系特定部分。这些结果为植物真菌病原体的比较基因组学研究，致病性演变以及宿主-病原体相互作用动力学基础的毒力因子奠定了坚实的基础，从而最终为镰刀菌病的防治提供了解决方案。