Artificial receptor-like structures such as molecular imprinted polymers (MIPs) are biomimetic molecules are used to replicate target specific antibody-antigen mechanism. In MIPs, selective binding of template molecule can be significantly correlated with lock and key mechanism, which play a major role in the drug delivery mechanism. The MIPs are biocompatible with high efficiency and are considered in several drug delivery and biosensor applications besides continuous and controlled drug release leading to better therapeutics. There is a need to explore the potential synthetic methods to improve MIPs with respect to the imprinting capacity in cancer therapeutics. In this review, we focus on MIPs as drug delivery mechanism in cancer and the challenges related to their synthesis and applications.

人工受体样结构，例如分子印迹聚合物（MIP），是仿生分子，用于复制靶标特异性抗体-抗原机制。在MIP中，模板分子的选择性结合可以与锁和钥匙机制显着相关，锁和钥匙机制在药物递送机制中起主要作用。MIP具有高效的生物相容性，除了可连续且受控地释放药物以带来更好的治疗效果外，还在多种药物输送和生物传感器应用中得到了考虑。有必要探索潜在的合成方法来改善MIPs在癌症治疗剂中的印迹能力。在这篇综述中，我们将重点放在作为癌症药物输送机制的MIP以及与其合成和应用相关的挑战上。