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National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in México.
Journal of Alzheimer’s Disease ( IF 3.4 ) Pub Date : 2020-08-04 , DOI: 10.3233/jad-191015
Aldelmo Emmanuel Reyes-Pablo 1, 2 , B Berenice Campa-Córdoba 1, 2 , Nabil Itzi Luna-Viramontes 1, 2 , Miguel Ángel Ontiveros-Torres 3 , Ignacio Villanueva-Fierro 4 , Marely Bravo-Muñoz 1 , Bárbara Sáenz-Ibarra 5 , Oralia Barbosa 6 , Parménides Guadarrama-Ortíz 7 , Linda Garcés-Ramírez 2 , Fidel de la Cruz 2 , Charles R Harrington 8 , Sandra Martínez-Robles 1 , Erik González-Ballesteros 1 , George Perry 9 , Mar Pacheco-Herrero 10 , José Luna-Muñoz 1
Affiliation  

We recently developed the National Dementia Biobank in México (BioBanco Nacional de Demencias, BND) as a unit for diagnosis, research, and tissue transfer for research purposes. BND is associated with the Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico (UNAM), Mexico. The donation of fluids, brain, and other organs of deceased donors is crucial for understanding the underlying mechanisms of neurodegenerative diseases and for the development of successful treatment. Our laboratory research focuses on 1) analysis of the molecular processing of the proteins involved in those neurodegenerative diseases termed tauopathies and 2) the search for biomarkers for the non-invasive and early diagnosis of Alzheimer’s disease.

中文翻译:

国家痴呆症生物库:墨西哥神经退行性疾病的诊断和研究策略。

我们最近在墨西哥开发了国家痴呆症生物库(BioBanco Nacional de Demencias,BND),作为诊断,研究和组织转移的研究单位。BND与墨西哥国立墨西哥自治大学(UNAM)的Facultad de Estudios SuperioresCuautitlán合作。捐献已故捐献者的体液,大脑和其他器官对于理解神经退行性疾病的潜在机制和开发成功的治疗至关重要。我们的实验室研究侧重于1)分析与神经退行性疾病有关的蛋白质的分子加工过程,这些疾病被称为“ tauopathies”,以及2)寻找用于非侵入性和早期诊断阿尔茨海默氏病的生物标志物。
更新日期:2020-08-08
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