Objective:The main goal of this study was to examine the influence of hydroxyapatite (HAp) macroaggreate concentrations on thermal and mechanical properties of radioactive bone cement and to study the relation of glass transition Tg with its mechanical properties. Methods:The bone cement as (1-x)PMMA-xHAp binary system was prepared in six [x] distinct concentration parameters of 0.0 up to 0.5. The HAp was synthesized using a solgel procedure following calcination by thermal treatment. The composite was prepared in cold based (non-radioactive) mixing polymethyl methacrylate (PMMA) and HAp. Differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and mechanical compressive strength (CS) were used to measure the thermal and mechanical properties. Results:The DSC and TGA thermal profiles in function to concentration parameter [x] were presented. The CS lies in a range of 3.71–7.37 MPa and the glass transition temperature Tg = 126.27 °C. There was a direct relationship between the PMMA-HAp thermoplastic properties with mechanical and thermal properties in function of HAp concentrations. Conclusion:The specific PMMA-HAp composite, with a concentration ratio of 1:1 and HAp thermal treatment at the Tg, provides a material with a compression strength of 7.37 MPa and a suitable amount of porous similar to a trabecular bone, possible to apply in bone cement implants, whether they are radioactive or not.

中文翻译：

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羟基磷灰石对生物医学应用的PMMA-HAp水泥的影响。

目的：本研究的主要目的是研究羟基磷灰石（HAp）大骨料浓度对放射性骨水泥热力学性能的影响，并研究玻璃化转变温度Tg与其力学性能的关系。方法：以（0.0）至0.5的六个[x]不同浓度参数制备作为（1-x）PMMA-xHAp二元系统的骨水泥。在通过热处理煅烧之后，使用溶胶凝胶法合成HAp。该复合材料是在冷基（非放射性）混合聚甲基丙烯酸甲酯（PMMA）和HAp中制备的。差示扫描量热法（DSC），热重分析（TGA）和机械抗压强度（CS）用于测量热性能和机械性能。结果：给出了DSC和TGA相对于浓度参数[x]的热曲线。CS处于3.71–7.37 MPa的范围内，玻璃化转变温度Tg = 126.27°C。在HAp浓度的函数中，PMMA-HAp热塑性特性与机械和热特性之间存在直接关系。结论：特定的PMMA-HAp复合材料具有1：1的浓缩比和在Tg处进行HAp热处理，可提供抗压强度为7.37 MPa且具有与小梁骨相似的适量多孔性的材料，可以应用在骨水泥植入物中，无论是否具有放射性。在HAp浓度的函数中，PMMA-HAp热塑性特性与机械和热特性之间存在直接关系。结论：特定的PMMA-HAp复合材料具有1：1的浓缩比和在Tg处进行HAp热处理，可提供抗压强度为7.37 MPa且具有与小梁骨相似的适量多孔性的材料，可以应用在骨水泥植入物中，无论是否具有放射性。在HAp浓度的函数中，PMMA-HAp热塑性特性与机械和热特性之间存在直接关系。结论：特定的PMMA-HAp复合材料具有1：1的浓缩比和在Tg处进行HAp热处理，可提供抗压强度为7.37 MPa且具有与小梁骨相似的适量多孔性的材料，可以应用在骨水泥植入物中，无论是否具有放射性。