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Fibrogenesis in chronic murine colitis is independent of innate lymphoid cells.
Immunity, Inflammation and Disease ( IF 3.1 ) Pub Date : 2020-06-21 , DOI: 10.1002/iid3.321
Brecht Creyns 1, 2 , Jonathan Cremer 1, 2 , Gert De Hertogh 3 , Louis Boon 4 , Marc Ferrante 2, 5 , Séverine Vermeire 2, 5 , Gert Van Assche 2, 5 , Jan L Ceuppens 1 , Christine Breynaert 1, 6
Affiliation  

Insight in the pathogenesis of intestinal fibrosis is an unmet medical need in inflammatory bowel diseases. Studies in murine models and human organ fibrosis point to a potential role of innate lymphoid cells (ILC) in chronic intestinal inflammation and fibrosis.

中文翻译:

慢性小鼠结肠炎中的纤维生成与先天淋巴细胞无关。

深入了解肠纤维化的发病机制是炎症性肠病中未满足的医疗需求。对小鼠模型和人体器官纤维化的研究表明先天淋巴细胞 (ILC) 在慢性肠道炎症和纤维化中具有潜在作用。
更新日期:2020-08-10
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