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Invited Article: Emerging soft bioelectronics for cardiac health diagnosis and treatment
APL Materials ( IF 5.3 ) Pub Date : 2019-03-01 , DOI: 10.1063/1.5060270
Faheem Ershad 1 , Kyoseung Sim 2 , Anish Thukral 3 , Yu Shrike Zhang 4 , Cunjiang Yu
Affiliation  

Cardiovascular diseases are among the leading causes of death worldwide. Conventional technologies for diagnosing and treating lack the compliance and comfort necessary for those living with life-threatening conditions. Soft electronics presents a promising outlet for conformal, flexible, and stretchable devices that can overcome the mechanical mismatch that is often associated with conventional technologies. Here, we review the various methods in which electronics have been made flexible and stretchable, to better interface with the human body, both externally with the skin and internally with the outer surface of the heart. Then, we review soft, wearable, noninvasive heart monitors designed to be attached to the chest or other parts of the body for mechano-acoustic and electrophysiological sensing. A common method of treatment for various abnormal heart rhythms involves catheter ablation procedures and we review the current soft bioelectronics that can be placed on the balloon or head of the catheter. Cardiac mapping is integral to determine the state of the heart; we discuss the various parameters for sensing aside from electrophysiological sensing, such as temperature, pH, strain, and tactile sensing. Finally, we review the soft devices that harvest energy from the natural and spontaneous beating of the heart by converting its mechanical motion into electrical energy to power implants.

中文翻译:

特邀文章:用于心脏健康诊断和治疗的新兴软生物电子学

心血管疾病是世界范围内导致死亡的主要原因之一。用于诊断和治疗的传统技术缺乏对那些生活在危及生命的疾病中的人来说所需的依从性和舒适度。软电子为共形、柔性和可拉伸设备提供了一个有前途的出口,可以克服通常与传统技术相关的机械失配。在这里,我们回顾了使电子产品变得灵活和可拉伸的各种方法,以更好地与人体接触,包括外部与皮肤和内部与心脏的外表面。然后,我们回顾了设计用于连接到胸部或身体其他部位以进行机械声学和电生理传感的柔软、可穿戴、无创心脏监测器。治疗各种异常心律的常用方法包括导管消融程序,我们回顾了当前可以放置在球囊或导管头部的软生物电子学。心脏测绘是确定心脏状态不可或缺的一部分;我们讨论了除电生理传感之外的各种传感参数,例如温度、pH、应变和触觉传感。最后,我们回顾了通过将机械运动转化为电能为植入物提供动力来从心脏的自然和自发跳动中获取能量的软设备。我们讨论了除电生理传感之外的各种传感参数,例如温度、pH、应变和触觉传感。最后,我们回顾了通过将机械运动转化为电能为植入物提供动力来从心脏的自然和自发跳动中获取能量的软设备。我们讨论了除电生理传感之外的各种传感参数,例如温度、pH、应变和触觉传感。最后,我们回顾了通过将机械运动转化为电能为植入物提供动力来从心脏的自然和自发跳动中获取能量的软设备。
更新日期:2019-03-01
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