BACKGROUND Left ventricular aneurysm (LVA) is indicator of high morbidity in Chagas’ disease. A cross-sectional study performed identified LVA in 18.8% of the chronic chagasic patients (CCP). OBJECTIVE Determine the risk of death of patients with chronic chagasic cardiopathy (CCC) and LVA in 24-year interval. MATERIAL AND METHODS In 1995 a cohort of 298 CCP was evaluated by anamnesis, physical examination, EKG and ECHO and classified in groups: G0 = 86 without cardiopathy; G1 = 156 with cardiopathy without LVA and G2 = 56 with cardiopathy and LVA. 38 patients of G0 and G1 used benznidazole. Information about the deaths was obtained in the notary, death certificates, hospital records and family members. FINDINGS Were registered 113 deaths (37.9%): 107 (35.9%) attributed to cardiopathy and 6 (2.0%) to other causes (p < 0.05). Amongst these 107 deaths, 10 (11.6%) occurred in G0; 49 (31.4%) occurred in G1 and 48 (85.7%) occurred in G2 (p < 0.05). The risk of death was 2.7 and 7.4 times significantly higher in G2, than in G1 and G0, respectively. CONCLUSION Chronic chagasic patients with LVA and ejection fraction < 45% have a higher risk of death than those without.

中文翻译：

---

巴西米纳斯吉拉斯州Virgem da Lapa的恰加斯病：24年内出现左心室动脉瘤和死亡风险。

背景技术左心室动脉瘤（LVA）是恰加斯病高发病率的指标。进行的一项横断面研究确定了18.8％的慢性Chagasic患者（CCP）中的LVA。目的确定24年间隔内的慢性Chagasic型心脏病（CCC）和LVA患者的死亡风险。材料与方法1995年，对一组298位CCP进行了回顾性检查，体格检查，EKG和ECHO评估，并分为以下几类：G0 = 86（无心脏病）。对于没有LVA的心脏病，G1 = 156；对于患有LVA的心脏病，G2 = 56。G0和G1的38例患者使用了苯硝唑。有关死亡的信息可通过公证，死亡证明，医院记录和家庭成员获得。研究结果表明，有113例死亡（37.9％）：107例（35.9％）归因于心脏病，6例（2.0％）归因于其他原因（p <0.05）。在这107例死亡中，有10例（11.6％）发生在G0。G1发生49（31.4％），G2发生48（85.7％）（p <0.05）。G2的死亡风险分别比G1和G0高出2.7和7.4倍。结论LVA且射血分数<45％的慢性chagas病患者的死亡风险要高于无此病的患者。