Uncertainties in thyroid doses due to I intake were evaluated for 2,239 subjects in a case-control study of thyroid cancer following exposure to Chernobyl fallout during childhood and adolescence carried out in contaminated regions of Belarus and Russia. Using new methodological developments that became available recently, a Monte Carlo simulation procedure was applied to calculate 1,000 alternative vectors of thyroid doses due to I intake for the study population of 2,239 subjects accounting for sources of shared and unshared errors. An overall arithmetic mean of the stochastic thyroid doses in the study was estimated to be 0.43 Gy and median dose of 0.16 Gy. The arithmetic mean and median of deterministic doses estimated previously for 1,615 of 2,239 study subjects were 0.48 Gy and 0.20 Gy, respectively. The geometric standard deviation of individual stochastic doses varied from 1.59 to 3.61 with an arithmetic mean of 1.94 and a geometric mean of 1.89 over all subjects of the study. These multiple sets of thyroid doses were used to update radiation-related thyroid cancer risks in the study population exposed to I after the Chernobyl accident.

中文翻译：

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儿童时期暴露于切尔诺贝利放射性尘埃 131I 的人群中甲状腺癌病例对照研究的辐射剂量的不确定性。


在白俄罗斯和俄罗斯污染地区开展的一项甲状腺癌病例对照研究中，对 2,239 名受试者在儿童和青少年时期接触切尔诺贝利放射性尘埃后因 I 摄入引起的甲状腺剂量的不确定性进行了评估。利用最近出现的新方法学进展，应用蒙特卡罗模拟程序计算 2,239 名受试者的研究人群由于 I 摄入量而产生的 1,000 个替代甲状腺剂量向量，并考虑了共享和非共享误差的来源。研究中随机甲状腺剂量的总体算术平均值估计为 0.43 Gy，中位剂量为 0.16 Gy。先前估计 2,239 名研究对象中的 1,615 名确定性剂量的算术平均值和中位数分别为 0.48 Gy 和 0.20 Gy。所有研究对象的个体随机剂量的几何标准差为 1.59 至 3.61，算术平均值为 1.94，几何平均值为 1.89。这些多组甲状腺剂量用于更新切尔诺贝利事故后暴露于 I 的研究人群中与辐射相关的甲状腺癌风险。