Background:Parkinson’s disease (PD) frequently causes progressive deterioration in speech, voice and cognitive aspects of communication. These affect wellbeing and quality of life and are associated with caregiver strain and burden. Therapeutic singing groups can ameliorate PD-related communicationdisorders and increase social interaction and wellbeing for caregivers and care recipients. Objective:To analyse the effects of ParkinSong group singing sessions on Parkinson’s communication and wellbeing outcomes for people with PD and caregivers over 12 months. Methods:A 4-armed controlled clinical trial compared ParkinSong with active non-singing control conditions over 12 months. Two dosage levels (weekly versus monthly) were available for each condition. ParkinSong comprised high-effort vocal, respiratory and speech exercises, group singing, and social interaction. PD-specific outcomes included vocal loudness, speech intelligibility, maximum phonation time, respiratory muscle strength, and voice related quality of life (QoL). Wellbeing outcomes were also measured for caregivers and care recipients. Results:We recruited 75 people with PD and 44 caregivers who attended weekly ParkinSong, monthly ParkinSong, weekly control or monthly control groups. We found significant improvements in the primary outcome of vocal loudness (p = 0.032), with weekly singers 5.13 dB louder (p = 0.044) and monthly singers 5.69 dB louder (p = 0.015) than monthly controls at 12 months. ParkinSong participants also showed greater improvements in voice-related QoL and anxiety. Caregivers who attended ParkinSong showed greater reductions in depression and stress scores. Conclusions:This 12-month controlled clinical trial of ParkinSong demonstrated improvements in speech loudness and voice-related QoL for participants with PD, and enhanced wellbeing for both caregivers and care recipients. No adverse effects were reported over 12 months and improvements were sustained.

中文翻译：

---

ParkinSong：帕金森病治疗性歌唱组的 12 个月对照试验的结果。

背景：帕金森病 (PD) 经常导致言语、声音和沟通认知方面的进行性恶化。这些会影响幸福感和生活质量，并与照顾者的压力和负担有关。治疗性歌唱团体可以改善与 PD 相关的沟通障碍，并增加看护者和被看护者的社交互动和幸福感。目的：分析 ParkinSong 集体歌唱课程对 12 个月内帕金森患者和护理人员的帕金森沟通和健康结果的影响。方法：一项 4 臂对照临床试验在 12 个月内将 ParkinSong 与主动非唱歌对照条件进行了比较。每种情况都有两种剂量水平（每周和每月）。ParkinSong 包括高强度的声乐、呼吸和言语练习、合唱、和社交互动。PD 特定的结果包括声音响度、语音清晰度、最大发声时间、呼吸肌强度和与声音相关的生活质量 (QoL)。还测量了护理人员和护理对象的幸福感结果。结果：我们招募了 75 名 PD 患者和 44 名护理人员，他们参加了每周 ParkinSong、每月 ParkinSong、每周对照组或每月对照组。我们发现声音响度的主要结果有显着改善 (p = 0.032)，在 12 个月时，每周歌手的声音比每月的歌手高 5.13 dB (p = 0.044)，每月歌手的声音比每月的对照组高 5.69 dB (p = 0.015)。ParkinSong 参与者在与语音相关的 QoL 和焦虑方面也表现出更大的改善。参加 ParkinSong 的护理人员在抑郁和压力评分方面表现出更大的降低。结论：这项为期 12 个月的 ParkinSong 对照临床试验表明，PD 参与者的语音响度和与语音相关的 QoL 有所改善，并增强了看护者和被看护者的幸福感。12 个月内未报告任何不良反应，并且持续改善。