Cadmium, cobalt, copper, nickel, and zinc are the most common pollutant heavy metals that can be discharged into the marine environment with different sources. Whiting (Merlangius merlangus) and mullet (Mullus barbatus) were sampled in four seasons in a year to determine Cd, Co, Cu, Ni, and Zn levels in the muscle and to determine heavy metal resistance genes (MRGs) such as copA, czc, and ncc genes in coliform bacteria isolated from the fish. In both species, zinc was the most abundant metal, while Cd and the Co levels were scarce. Co level was significantly higher in summer in mullet than that of whiting (p < 0.001). The most prevalent MRGs was determined as copA (46.2%) followed by czc (35.8%) and ncc (17.9%). Increased Co and Ni level in the muscle significantly affected the presence of ncc gene in bacteria, while the presence of ncc and copA genes was affected by Ni and Cu levels found in the fish muscle. There was a significant positive correlation between Cd level in the muscle and presence of czc and ncc gene in the bacteria (p < 0.029). When the levels of Cu, Zn, and Cd increased in the muscle of the fish, occurrence of MRGs genes was increased significantly (p < 0.0001). A strong positive correlation was found between heavy metal resistance levels in fish and the prevalence of E. coli and coliforms that harbor heavy metal resistance genes which will be a problem in aquaculture, aquatic ecosystem, and public health.

中文翻译：

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鱼类肌肉中重金属积累与鱼类分离细菌中重金属抗性基因的关系。

镉、钴、铜、镍和锌是最常见的污染物重金属，可通过不同来源排放到海洋环境中。在一年中的四个季节对白鳍鱼 (Merlangius merlangus) 和鲻鱼 (Mullus barbatus) 进行采样，以确定肌肉中的 Cd、Co、Cu、Ni 和 Zn 水平并确定重金属抗性基因 (MRG)，例如 copA、czc和从鱼中分离的大肠菌中的 ncc 基因。在这两个物种中，锌是最丰富的金属，而 Cd 和 Co 含量很少。夏季鲻鱼的 Co 水平显着高于鳕鱼（p < 0.001）。最普遍的 MRG 被确定为 copA (46.2%)，其次是 czc (35.8%) 和 ncc (17.9%)。肌肉中 Co 和 Ni 水平的增加显着影响了细菌中 ncc 基因的存在，而 ncc 和 copA 基因的存在受鱼肌肉中 Ni 和 Cu 水平的影响。肌肉中的 Cd 水平与细菌中 czc 和 ncc 基因的存在之间存在显着的正相关（p < 0.029）。当鱼肌肉中Cu、Zn和Cd水平增加时，MRGs基因的出现显着增加（p < 0.0001）。发现鱼类的重金属抗性水平与含有重金属抗性基因的大肠杆菌和大肠菌群的流行之间存在很强的正相关，这将成为水产养殖、水生生态系统和公共健康的一个问题。鱼肌肉中Zn和Cd增加，MRGs基因的出现显着增加（p < 0.0001）。发现鱼类的重金属抗性水平与含有重金属抗性基因的大肠杆菌和大肠菌群的流行之间存在很强的正相关，这将成为水产养殖、水生生态系统和公共健康的一个问题。鱼肌肉中Zn和Cd增加，MRGs基因的出现显着增加（p < 0.0001）。发现鱼类的重金属抗性水平与含有重金属抗性基因的大肠杆菌和大肠菌群的流行之间存在很强的正相关，这将成为水产养殖、水生生态系统和公共健康的一个问题。