Background

Limited information is available on the effect of anaphylaxis, a severe, potentially life-threatening allergic reaction, in the elderly population.

Objective

To elucidate the frequency of anaphylaxis and the demographic characteristics of elderly patients admitted to New York hospitals from 2000 to 2010.

Methods

A retrospective analysis of hospitalized patients aged 65 years and older in New York from 2000 to 2010 was conducted using the Statewide Planning and Research Cooperative System, a statewide administrative database. Cases were identified using anaphylaxis International Classification of Diseases, Ninth Revision (ICD-9) codes or an ICD-9–based diagnostic algorithm incorporating the National Institutes of Allergy and Infectious Disease diagnostic criteria. The χ² test was used to measure the association between demographic characteristics and group membership. Regression was used to model group and age as a function of hospital rates.

Results

A total of 3673 hospitalizations were analyzed. Anaphylaxis ICD-9 codes identified 1790 cases (48.7%), the algorithms identified 1701 cases (46.3.%), and 182 cases (5.0%) were identified by both. Hospitalization rates increased significantly during this period (P < .001). Women comprised 61.5% and people of white race comprised 69.8% of the sample. Distribution by age differed by ascertainment method (ICD-9 vs algorithm) among the early-old group (65-74 years of age; 53.8% vs 41.8%) and among the late-old group (≥85 years of age; 11.2% vs 19.3%).

Conclusion

Hospitalization rates and anaphylaxis cases increased during the study period among the hospitalized elderly population of New York. Relying on anaphylaxis ICD-9 codes alone missed approximately half of possible cases. The identification and possibly the effect of anaphylaxis among the elderly population may differ, depending on age, race, payer, New York County, and disposition.

中文翻译：

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2000年至2010年纽约州老年人过敏反应的病例。

背景

关于过敏反应（一种严重的，可能威胁生命的过敏反应）在老年人群中的作用的信息有限。

目的

为了阐明过敏反应的频率和从2000年至2010年入住纽约医院的老年患者的人口统计学特征。

方法

使用州范围内的行政数据库“州范围计划与研究合作系统”，对2000年至2010年纽约65岁及以上的住院患者进行了回顾性分析。使用过敏性国际疾病分类，第九修订版（ICD-9）代码或结合了美国国家过敏和传染病研究所诊断标准的基于ICD-9的诊断算法来鉴定病例。的χ ²检验来测量人口统计学特征和组成员之间的关联。回归用于根据住院率对人群和年龄进行建模。

结果

共分析了3673例住院病例。过敏性ICD-9代码识别出1790例（48.7％），算法识别出1701例（46.3。％），并且两者均识别出182例（5.0％）。在此期间，住院率显着增加（P <.001）。女性占61.5％，白人占69.8％。在早期组（65-74岁； 53.8％vs 41.8％）和晚期组（≥85岁； 11.2％）中，根据确定方法（ICD-9与算法）的年龄分布有所不同。 vs 19.3％）。

结论

在研究期间，纽约住院的老年人口的住院率和过敏反应病例增加。仅依靠过敏反应ICD-9代码就错过了大约一半的可能病例。老年人中过敏反应的识别和影响可能会有所不同，具体取决于年龄，种族，付款人，纽约县和处置方式。