Polymyxins play a significant role against carbapenem-resistant Enterobacteriaceae (CRE). A total of 121 clinical samples yielded growth of CRE that were included in the study. Rapid Polymyxin NP test was performed on all the isolates as described by Nordmann P et al. and results were compared with broth microdilution method. Majority of the isolates were Klebsiella pneumoniae (70.2%) followed by Escherichia coli (17.4%). A total of 71 isolates were found resistant and 50 as susceptible by broth microdilution. Sensitivity and specificity of rapid polymyxin NP test were found to be 97.2% and 100%, respectively. Our study concluded that rapid polymyxin NP test is reliable and can be used as an alternative to broth microdilution in resource limited settings.

多粘菌素在抗碳青霉烯的肠杆菌科（CRE）中起着重要作用。总共121个临床样本产生了CRE的生长，该样本包括在研究中。如Nordmann P等人所述，对所有分离物进行快速多粘菌素NP测试。并将结果与​​肉汤微量稀释法进行比较。多数分离株是肺炎克雷伯菌（70.2％），其次是大肠杆菌（17.4％）。通过肉汤微稀释，发现总共71株分离株具有抗性，其中50株易感。快速多粘菌素NP检测的敏感性和特异性分别为97.2％和100％。我们的研究得出结论，快速多粘菌素NP检测是可靠的，并且可以在资源有限的环境中用作肉汤微量稀释的替代方法。