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Electrospun PCL-based nanofibers Arrabidaea chica Verlot - Pterodon pubescens Benth loaded: synergic effect in fibroblast formation.
Biomedical Materials ( IF 3.9 ) Pub Date : 2020-09-18 , DOI: 10.1088/1748-605x/ab9bb1
Tais Helena Costa Salles 1 , Fabiana Volpe-Zanutto 2, 3 , Ilza Maria de Oliveira Sousa 4 , Daisy Machado 5 , Ana Caroline Zanatta 6 , Wagner Vilegas 6 , Marcelo Lancellotti 5 , Mary Ann Foglio 5 , Marcos Akira d'Ávila 1
Affiliation  

The guided tissue regeneration (GTR) technique can be applied in dentistry and other medical specializations, such as orthopedics. In modern dentistry, GTR has been used in periodontics and implantology to treat periodontal defects, to reconstruct lost, damaged and atrophied bone tissue in dental implant procedures, and to preserve alveolar bases after tooth extraction. In order to create and improve new therapies and to develop new biomaterials that restore, improve and prevent aggravation of compromised tissue function, poly (ϵ-caprolactone) (PCL) polymer membranes were obtained by the electrospinning process and were associated with two plant extracts: Pterodon pubescens Benth ( P. pubescens ) and Arrabidaea chica Verlot ( A. chica ) which are characterized by their pharmacological activities of anti-inflammatory and healing actions, respectively. Fiber morphology was analyzed using scanning electron microscopy (SEM), where fiber average diameter was m...

中文翻译:


基于电纺 PCL 的纳米纤维 Arrabidaea chica Verlot - Pterodon pubescens Benth 负载:在成纤维细胞形成中的协同作用。



引导组织再生(GTR)技术可应用于牙科和其他医学专业,例如骨科。在现代牙科中,GTR 已用于牙周病学和种植学,以治疗牙周缺损,重建牙种植手术中丢失、损坏和萎缩的骨组织,以及在拔牙后保留牙槽底。为了创造和改进新疗法,并开发恢复、改善和防止受损组织功能恶化的新生物材料,通过静电纺丝工艺获得了聚(ε-己内酯)(PCL)聚合物膜,并与两种植物提取物结合: Pterodon pubescens Benth (P. pubescens) 和 Arrabidaea chica Verlot (A. chica) 的特点分别是抗炎和治疗作用的药理活性。使用扫描电子显微镜 (SEM) 分析纤维形态,其中纤维平均直径为 m...
更新日期:2020-09-20
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