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Interleukin-22 in urinary tract disease - new experimental directions.
Clinical & Translational Immunology ( IF 4.6 ) Pub Date : 2020-06-07 , DOI: 10.1002/cti2.1143 Molly A Ingersoll 1, 2 , Malcolm R Starkey 3, 4
Clinical & Translational Immunology ( IF 4.6 ) Pub Date : 2020-06-07 , DOI: 10.1002/cti2.1143 Molly A Ingersoll 1, 2 , Malcolm R Starkey 3, 4
Affiliation
Interleukin (IL)-22 is expressed by immune cells in the urinary tract and IL-22 receptor is expressed in urothelium and renal tubule cells. IL-22 can be specifically targeted in the urinary tract or conditionally depleted in mice and targeted therapeutically in humans.
中文翻译:
白细胞介素22在泌尿道疾病中-新的实验方向。
白细胞介素(IL)-22在尿道中由免疫细胞表达,白介素22受体在尿路上皮和肾小管细胞中表达。IL-22可以在尿道中特异性靶向或在小鼠中有条件地消耗,而在人类中则是治疗性靶向。
更新日期:2020-06-07
中文翻译:
白细胞介素22在泌尿道疾病中-新的实验方向。
白细胞介素(IL)-22在尿道中由免疫细胞表达,白介素22受体在尿路上皮和肾小管细胞中表达。IL-22可以在尿道中特异性靶向或在小鼠中有条件地消耗,而在人类中则是治疗性靶向。