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Towards an understanding of the avian virome.
Journal of General Virology ( IF 3.6 ) Pub Date : 2020-08-01 , DOI: 10.1099/jgv.0.001447
Sarah François 1 , Oliver G Pybus 1, 2
Affiliation  

The last two decades have seen the rise of viromics, the study of viral communities through the detection and characterization of virus genome sequences. Here we systematically review and summarize the scope and limitations of our current understanding of avian viromes, in both domesticated and wild-bird populations. We compare this viromic work to the broader literature on avian prokaryotic microbiomes, and highlight the growing importance of structured sampling and experimental design for testing explanatory hypotheses. We provide a number of recommendations for sample collection and preliminary data analysis to guide the development of avian viromics. Avian viromes have the potential to inform disease surveillance in poultry and improve our understanding of the risk of zoonotic viruses to human health.

中文翻译:


了解禽病毒组。



过去二十年见证了病毒组学的兴起,病毒组学是通过病毒基因组序列的检测和表征来研究病毒群落。在这里,我们系统地回顾和总结了我们目前对家养鸟类和野生鸟类病毒组的了解的范围和局限性。我们将这项病毒学工作与更广泛的鸟类原核微生物组文献进行比较,并强调结构化采样和实验设计对于检验解释性假设日益重要。我们提供了一些有关样本收集和初步数据分析的建议,以指导禽病毒组学的发展。禽病毒组有可能为家禽疾病监测提供信息,并提高我们对人畜共患病毒对人类健康风险的了解。
更新日期:2020-08-27
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