Ferrocene-substituted 2,5-di(thienyl)pyrrole (SNS-Fc) was electrochemically polymerized in the presence and absence of 3,4-ethylenedioxythiophene (EDOT) and utilized for biosensing upon immobilization of glucose oxidase (GOD) through cross-linking. The two biosensors, homopolymer P(SNS-Fc) and copolymer-based P(SNS-Fc-co-EDOT) were evaluated by comparison in terms of analytical performance. Due to the conducting-redox active nature of the films, the study was able to consider the developed sensors both as “first generation,” monitoring H 2 O 2 oxidation and as “second generation,” using the optimum potential for ferrocene oxidation. The difference in performance at these two working potentials served as assessment of the influence of ferrocene moiety within the conducting film. In the scope of further improvement, carbon nanotubes (MWCNTs) were incorporated in both type systems. This improved the detection efficiency leading to extension of linear range up to ...

中文翻译：

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无试剂安培葡萄糖生物传感器：二茂铁系留和共聚合

二茂铁取代的2,5-二（噻吩基）吡咯（SNS-Fc）在存在和不存在3,4-乙撑二氧噻吩（EDOT）的情况下进行电化学聚合，并通过交联固定葡萄糖氧化酶（GOD）后用于生物传感。通过比较在分析性能方面评估了两种生物传感器，均聚物P（SNS-Fc）和基于共聚物的P（SNS-Fc-co-EDOT）。由于薄膜具有导电氧化还原活性，因此该研究能够将开发的传感器视为“第一代”，监测H 2 O 2氧化，并将其视为“第二代”，并利用二茂铁氧化的最佳电势。在这两个工作电位下的性能差异可用来评估导电膜中二茂铁部分的影响。在进一步改进的范围内，两种类型的系统中都包含了碳纳米管（MWCNT）。这提高了检测效率，导致线性范围扩展到...