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Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages.
Frontiers in Cellular and Infection Microbiology ( IF 4.6 ) Pub Date : 2020-06-10 , DOI: 10.3389/fcimb.2020.00356
Byron Freire-Paspuel 1 , Patricio Vega-Mariño 2 , Alberto Velez 2 , Paulina Castillo 2 , Eliana Elizabeth Gomez-Santos 3 , Marilyn Cruz 2 , Miguel Angel Garcia-Bereguiain 1
Affiliation  

CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries.

更新日期:2020-06-23
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