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Smart Drug Delivery: Ultraviolet Light‐Assisted Electrospinning of Core–Shell Fully Cross‐Linked P(NIPAAm‐co‐NIPMAAm) Hydrogel‐Based Nanofibers for Thermally Induced Drug Delivery Self‐Regulation (Adv. Mater. Interfaces 12/2020)
Advanced Materials Interfaces ( IF 4.3 ) Pub Date : 2020-06-23 , DOI: 10.1002/admi.202070064
Sylwia Pawłowska 1 , Chiara Rinoldi 1 , Paweł Nakielski 1 , Yasamin Ziai 1 , Olga Urbanek 1 , Xiaoran Li 2 , Tomasz Aleksander Kowalewski 1 , Bin Ding 2 , Filippo Pierini 1
Affiliation  

In article number 2000247 by Filippo Pierini and co‐workers, an electrospun biomimetic nanoplatform for self‐regulated drug delivery is developed. Such smart drug delivery system relies on the confinement of a stimuli‐responsive hydrogel within the core of a hierarchical electrospun core‐shell fibrous structure. The delivery of loaded bioactive molecules is self‐modulated through structural changes triggered by a temperature‐regulated cascade.
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中文翻译:

智能药物输送:核壳完全交联的P(NIPAAm-co-NIPMAAm)水凝胶基纳米纤维的紫外光辅助静电纺丝,用于热诱导药物输送自我调节(Adv。Mater。Interfaces 12/2020)

Filippo Pierini及其同事在编号为2000247的文章中,开发了一种用于自调控药物递送的电纺丝仿生纳米平台。这种智能的药物输送系统依赖于刺激性水凝胶在分级电纺芯-壳纤维结构核心内的限制。负载的生物活性分子的传递通过温度调节级联反应触发的结构变化而自我调节。
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更新日期:2020-06-23
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