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Bile reflux in patients with nerd is associated with more severe heartburn and lower values of mean nocturnal baseline impedance and chemical clearance.
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2020-06-22 , DOI: 10.1111/nmo.13919
Nicola de Bortoli 1 , C Prakash Gyawali 2 , Marzio Frazzoni 3 , Salvatore Tolone 4 , Leonardo Frazzoni 5 , Eleonora Vichi 1 , Pierfrancesco Visaggi 1 , Massimo Bellini 1 , Elisa Marabotto 6 , Roberto Penagini 7, 8 , Vincenzo Savarino 6 , Santino Marchi 1 , Edoardo V Savarino 9
Affiliation  

Mean nocturnal baseline impedance (MNBI) and postreflux swallow‐induced peristaltic wave (PSPW) index are novel impedance‐based markers of reflux, but the effect of bile reflux on these metrics is unknown. The aim of this study was to evaluate bile reflux, MNBI, and PSPW index in patients with endoscopy‐negative GERD partially responsive to PPI therapy.

中文翻译:

书呆子患者的胆汁反流与更严重的胃灼热和夜间平均基线阻抗和化学清除率的较低值有关。

平均夜间基线阻抗 (MNBI) 和反流后吞咽诱导的蠕动波 (PSPW) 指数是新的基于阻抗的反流标志物,但胆汁反流对这些指标的影响尚不清楚。本研究的目的是评估对 PPI 治疗有部分反应的内窥镜检查阴性 GERD 患者的胆汁反流、MNBI 和 PSPW 指数。
更新日期:2020-06-22
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