We report a simple and sensitive voltammetric sensor for the determination of chlorpromazine (CPZ) based on Ni−Al layered double hydroxide (NiAlLDH) modified glassy carbon electrode (GCE). NiAlLDH was simply electrodeposited on GCE surface in a very short time. The response linear range was 1×10⁻³–1×10⁻⁹ mol L⁻¹, with a detection limit of 1×10⁻⁹ mol L⁻¹. The NiAlLDH film showed well defined and well separate peaks for dopamine, ascorbic acid, uric acid and CPZ in the same solution. The proposed electrode was used to measure the active pharmaceutical ingredient of CPZ tablet as a real sample.

中文翻译：

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层状双氢氧化物修饰玻碳电极作为纳米催化剂测定盐酸氯丙嗪

我们报告了一种基于Ni-Al层状双氢氧化物（NiAlLDH）修饰玻碳电极（GCE）的简单而灵敏的伏安传感器，用于测定氯丙嗪（CPZ）。NiAlLDH可以在很短的时间内简单地电沉积在GCE表面。响应线性范围为1×10 ^-3 –1×10 ^-9  mol L ^-1，检测极限为1×10 ^-9  mol L ^-1。NiAlLDH膜在同一溶液中显示出多巴胺，抗坏血酸，尿酸和CPZ的清晰定义和独立的峰。所建议的电极用于测量CPZ片剂的活性药物成分（作为真实样品）。