Background

Dietary fibers (DFs) are known as potential formulations in human health due to their beneficial effects in control of life-threatening chronic diseases including cardiovascular disease (CVD), diabetes mellitus, obesity and cancer. In recent decades scientists around the globe have shown tremendous interest to evaluate the interplay between DFs and gastrointestinal (GIT) microbiota. Evidences from various epidemiological and clinical trials have revealed that DFs modulate formation and metabolic activities of the microbial communities residing in the human GIT which in turn play significant roles in maintaining health and well-being. Furthermore, interestingly, a rapidly growing literature indicates success of DFs being prebiotics in immunomodulation, namely the stimulation of innate, cellular and humoral immune response, which could also be linked with their significant roles in modulation of the probiotics (live beneficial microorganisms).

Scope and approach

The main focus of the current review is to expressively highlight the importance of DFs being prebiotics in human health in association with their influence on gut microbiota. Now in order to significantly achieve the promising health benefits from these prebiotics, it is aimed to develop novel formulations to enhance and scale up their efficacy. Therefore, finally, herein unlike previously published articles, we highlighted different kinds of prebiotic and probiotic formulations which are being regarded as hot research topics among the scientific community now a days.

Conclusion

The information in this article will specifically provide a platform for the development of novel functional foods the demands for which has risen drastically in recent years.

中文翻译：

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益生元膳食纤维和益生菌对人类健康的影响：特别关注其封装配方的最新进展。

背景

膳食纤维 (DF) 被认为是人类健康的潜在配方，因为它们在控制危及生命的慢性疾病（包括心血管疾病 (CVD)、糖尿病、肥胖症和癌症）方面具有有益作用。近几十年来，全球科学家对评估 DF 与胃肠道 (GIT) 微生物群之间的相互作用表现出极大兴趣。来自各种流行病学和临床试验的证据表明，DFs 调节存在于人类 GIT 中的微生物群落的形成和代谢活动，而这反过来又在维持健康和福祉方面发挥重要作用。此外，有趣的是，越来越多的文献表明 DF 成功地成为免疫调节中的益生元，即刺激先天、细胞和体液免疫反应，

范围和方法

当前审查的主要重点是明确强调 DF 作为益生元对人类健康的重要性及其对肠道微生物群的影响。现在，为了从这些益生元中显着实现有前途的健康益处，旨在开发新的配方以增强和扩大其功效。因此，最后，与之前发表的文章不同，我们强调了不同种类的益生元和益生菌制剂，这些制剂如今被视为科学界的热门研究课题。

结论

本文中的信息将专门为近年来需求急剧上升的新型功能性食品的开发提供平台。