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Two new lignans from Anemone vitifolia buch.-Ham. and their anti-inflammatory activity
Phytochemistry Letters ( IF 1.3 ) Pub Date : 2020-06-23 , DOI: 10.1016/j.phytol.2020.06.001
Lin-Yun Mou , Hai-Yan Wu , Li-Jiao Hu , Min Wei , Jian-Long Li , Gan-Peng Li

Two new lignans (12), together with two known lignans (34), were isolated from the whole herb of Anemone vitifolia. The structures were identified based on extensive spectroscopic data analysis and comparison with reported data. All compounds of this plant were reported for the first time. In vitro test, all compounds were evaluated for their anti-inflammatory activity via calculating the production of nitric oxide (NO) in lipopolysaccharide (LPS)-induced mouse macrophage cells-RAW 264.7.



中文翻译:

海葵银莲花中的两种新木脂素。及其抗炎活性

两个新的木脂素(1 - 2)中,用两个已知的木酚素(一起3 - 4)中,从全草中分离海葵vitifolia。根据广泛的光谱数据分析和与报告数据的比较来鉴定结构。首次报道了该植物的所有化合物。在体外测试中,通过计算脂多糖(LPS)诱导的小鼠巨噬细胞-RAW 264.7中一氧化氮(NO)的产生,评估了所有化合物的抗炎活性。

更新日期:2020-06-23
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