Metals are of serious concern due to their toxicity, persistency, and accumulation potential in aquatic animals. However, limited information is available on the combined effects of metal with temperature elevation, which is one of the future climate changes suggested for the oceans. In this study, the effect of temperature elevation was investigated by analyzing toxicity, bioconcentration, and antioxidant response in juvenile and adult marine mysids upon exposure to 20 °C and 25 °C for 48 h and 96 h. Based on LC₅₀ values, toxicity of metals was highly reliant on temperature, exposure period, and age. Elevation in temperature significantly increased the whole metal toxicity in juveniles. Bioconcentration was elevated by increasing exposure period and metal concentration. Significant elevation of malondialdehyde (MDA) and depletion of glutathione (GSH) was measured in juveniles, while significant elevation of both MDA and GSH was detected in adults. Subsequently, enzymatic activities of antioxidant enzymes in catalase (CAT) and superoxide dismutase (SOD) increased significantly in adults at 48 h and 96 h, whereas most activities were significantly lowered in juveniles at 96 h. These results suggest that the early life stage of marine mysids is more sensitive to the combined effect of metal and temperature than adult stage due to an impairment in the induction of the antioxidant defense system.

金属由于其毒性，持久性和在水生动物中的蓄积潜力而备受关注。但是，关于金属与温度升高的综合影响的信息很少，这是建议对海洋进行的未来气候变化之一。在这项研究中，通过分析在20°C和25°C下分别暴露48 h和96 h的少年和成年海洋类鱼类的毒性，生物浓度和抗氧化剂反应，研究了温度升高的影响。基于LC ₅₀值，金属的毒性高度依赖于温度，暴露时间和年龄。温度升高显着增加了幼鱼的全金属毒性。通过增加暴露时间和金属浓度可以提高生物浓度。在少年中，丙二醛（MDA）显着升高，谷胱甘肽（GSH）耗竭，而成年人中MDA和GSH显着升高。随后，成年人在48 h和96 h的过氧化氢酶（CAT）和超氧化物歧化酶（SOD）中的抗氧化酶的酶活性显着增加，而在96 h的少年中，大多数活性显着降低。