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First reported case of Gilbertella persicaria in human stool: outcome of a community study from Segamat, Johor, Malaysia
Brazilian Journal of Microbiology ( IF 2.2 ) Pub Date : 2020-06-23 , DOI: 10.1007/s42770-020-00323-z
Marie Andrea Laetitia Huët 1 , Li Wen Wong 1 , Calvin Bok Sun Goh 1 , Kuan Shion Ong 1 , Jacky Dwiyanto 1 , Daniel Reidpath 2, 3 , Sui Mae Lee 1 , Sadequr Rahman 1, 4 , Joash Ban Lee Tan 1
Affiliation  

Species of fungi belonging to the order Mucorales can be found everywhere in the environment. Gilbertella persicaria, which belongs to this order, have often been isolated from fruits and in water systems. However, there has been no report of isolation of this fungus from human samples. During a gut mycobiome study, from the Segamat community, Gilbertella persicaria was isolated from a human fecal sample and was characterized through a series of morphological assessment, biochemical tests, and molecular techniques. The isolate produced a white velvety surface that turned grayish after 24 h. Although no biofilm production was observed, the results indicated that the isolate could form calcium oxalate crystals, produced urease, and was resistant to low pH. The isolate was sensitive to amphotericin but resistant to voriconazole and itraconazole. The features of this fungus that could help in its survival in the human gut are also discussed.

中文翻译:

首例报告的人类粪便中的白粉虱:来自马来西亚柔佛州昔加末的社区研究结果

属于毛霉目真菌的物种在环境中随处可见。Gilbertella persicaria 属于该目,经常从水果和水系统中分离出来。然而,没有从人类样本中分离出这种真菌的报道。在一项肠道菌群研究中,从 Segamat 群落中分离出桃金针虫,并通过一系列形态学评估、生化测试和分子技术对其进行了表征。分离物产生白色天鹅绒般的表面,24 小时后变成灰色。虽然没有观察到生物膜的产生,但结果表明分离物可以形成草酸钙晶体,产生脲酶,并且对低 pH 有抵抗力。该分离株对两性霉素敏感,但对伏立康唑和伊曲康唑耐药。
更新日期:2020-06-23
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