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Tolerance of 7% Hypertonic Saline in Pediatric Cystic Fibrosis Patients
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2020-06-17 , DOI: 10.1089/ped.2019.1127
Maria Talamo Guevara 1 , Susanna A McColley 2, 3, 4 , Karen Rychlik 2, 3, 4 , Adrienne P Savant 2, 3, 4
Affiliation  

Background: Clinical trials of 7% hypertonic saline (HTS) in cystic fibrosis (CF) show short- and long-term benefits, including improved pulmonary function and reduced exacerbation risk. Adverse effects of HTS include bronchospasm, and guidelines recommend tolerance be tested in a clinical environment before prescribing. We evaluated the rate of, and risk factors for, intolerance of HTS at a single pediatric CF program.

中文翻译:

小儿囊性纤维化患者对 7% 高渗盐水的耐受性

背景: 7% 高渗盐水 (HTS) 治疗囊性纤维化 (CF) 的临床试验显示出短期和长期益处,包括改善肺功能和降低恶化风险。HTS 的不良反应包括支气管痉挛,指南建议在开处方前在临床环境中测试耐受性。我们在单个儿科 CF 项目中评估了 HTS 不耐受的发生率和风险因素。
更新日期:2020-06-22
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