Glucose 6-phosphate dehydrogenase (G6PD) stands at the head of the pentose phosphate pathway, which is responsible for nucleotide synthesis. The identification and thorough validation of an improved G6PD inhibitor provide a valuable new tool compound for studying metabolism.

中文翻译：

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畅通的途径不值得研究。

葡萄糖6-磷酸脱氢酶（G6PD）位于磷酸戊糖途径的头，该途径负责核苷酸合成。改进的G6PD抑制剂的鉴定和全面验证为研究代谢提供了有价值的新工具化合物。