Abstract

We aimed to firstly examine the effects of nutrition and exercise training on irisin, Sema-3E, biochemical and inflammatory parameters in obese patients. This study was conducted using 37 individuals were divided into three groups according to body mass index (BMI) as non-obese, 1nd degree and 2nd degree obese individuals. Nutrition and exercise training were applied to groups for eight weeks. Insulin resistance decreased in non-obese and 1st degree obese subjects. HsCRP values decreased only in the second degree obese individuals. Adiponectin values were significantly decreased in all three groups. There was a negative correlation between serum adiponectin and plasma irisin levels both before and after treatment. Sema-3E levels increased significantly in only the first degree obese individuals, whereas plexin-D1 values did not change significantly in any group. Our findings indicate that nutrition and exercise training we apply improved both anthropometric measurements and biochemical parameters in obese and non-obese individuals.

摘要

我们旨在首先检查营养和运动训练对肥胖患者鸢尾素、Sema-3E、生化和炎症参数的影响。这项研究使用 37 个人进行，根据体重指数 (BMI) 分为三组，分别为非肥胖、1 度和 2 度肥胖个体。营养和运动训练被应用于小组八周。非肥胖和 1 度肥胖受试者的胰岛素抵抗降低。HsCRP 值仅在二级肥胖个体中降低。所有三组的脂联素值均显着降低。治疗前后血清脂联素与血浆鸢尾素水平呈负相关。Sema-3E 水平仅在一级肥胖个体中显着增加，而 plexin-D1 值在任何组中都没有显着变化。我们的研究结果表明，我们应用的营养和运动训练改善了肥胖和非肥胖个体的人体测量和生化参数。