ABSTRACT

Background: Children with cerebral palsy present age-driven development in gross motor skills and walking capacity.

Aims: To precisely monitor the 6-minute walk test (6MWT) in children with CP, GMFCS levels 1 and 2 over 6 months and to assess the effect of a 6-month rehabilitation program including whole-body vibration.

Methods: Retrospective analysis of data of 157 children with CP who received standardized rehabilitation (DRKS00011331). 6MWT was assessed at the start (M0) and end of the training (M6), as well as at a 6-month follow-up (M12). Centiles were created using the lambda-mu-sigma (LMS) method.

Results: We created 6MWT percentiles using data of all 157 children (M0 data). A medium treatment effect size (Cohen’s d = 0.69) was found (M6 and M12 data).

Conclusions: The generated centiles may help monitor 6MWT changes over 6 months. Combining WBV and conventional physiotherapy can significantly improve 6MWT in children with CP.

Abbreviations: 6MWT: 6-Minute Walk Test; CP: Cerebral palsy; ES: effect size; GMFCS: Gross Motor Function Classification System; GMFM-66: Gross Motor Function Measure 66; LOESS: locally weighted scatterplot smoothing; LMS: lambda-mu-sigma; MCID: minimal clinical important difference; SD: standard deviation; SRM: standardized response mean; WBV: whole-body vibration.

摘要

背景：患有脑瘫的儿童在总体运动技能和步行能力方面表现出年龄驱动的发展。

目的：在6个月内精确监测CP，GMFCS 1级和2级儿童的6分钟步行测试（6MWT），并评估包括全身振动在内的6个月康复计划的效果。

方法：回顾性分析157例接受标准化康复治疗的CP儿童的数据（DRKS00011331）。在训练开始（M0）和训练结束（M6）以及6个月的随访（M12）中评估了6MWT。使用lambda-mu-sigma（LMS）方法创建分数。

结果：我们使用所有157个孩子的数据（M0数据）创建了6MWT百分位。发现中等治疗效果大小（Cohen d = 0.69）（M6和M12数据）。

结论：产生的百分位数可能有助于监测6个月内6MWT的变化。WBV与常规理疗相结合可以显着改善CP儿童的6MWT。

缩写： 6MWT：6分钟步行测试；CP：脑瘫；ES：效果大小；GMFCS：运动功能总分类系统；GMFM-66：运动功能总测值66；黄土：局部加权散点图平滑；LMS：lambda-mu-sigma；MCID：最小的临床重要差异；SD：标准偏差；SRM：标准化响应平均值；WBV：全身振动。