Abstract

The present work reports ultrasound assisted and aluminized polyborate prompted green and efficient protocol for one pot four component Hantzsch condensation of aromatic aldehydes, dimedone, ethylcyanoacetate, and ammonium acetate to give hexahydroquinoline derivatives in ethanol:water (1:1) at room temperature. The key features of this protocol are sonochemical synthesis, environmental benign, short reaction time, recyclable catalyst, simple procedure, clean reaction, excellent product yields, and non-column purification. Additional importance of this method is an application of eco-sustainable aluminized polyborate as a catalyst, which is simply synthesized from easily available boric acid and aluminum trichloride. The catalyst was characterized by FT-IR, XRD, EDAX, and SEM techniques.

摘要

目前的工作报告了超声辅助和镀铝聚硼酸酯促进了绿色和有效的协议，用于一锅四组分 Hantzsch 缩合芳族醛、二甲酮、乙基氰基乙酸乙酯和乙酸铵，在室温下在乙醇：水 (1:1) 中得到六氢喹啉衍生物。该方案的主要特点是声化学合成、环境友好、反应时间短、催化剂可回收、程序简单、反应清洁、产品收率高、无柱纯化。这种方法的另一个重要之处是生态可持续的镀铝多硼酸盐作为催化剂的应用，它是由容易获得的硼酸和三氯化铝简单合成的。采用 FT-IR、XRD、EDAX 和 SEM 技术对催化剂进行了表征。