The carbonylation reaction represents one of the most powerful methods for the rapid build‐up of carbonyl structures and has widely applied in both academic and industry fields. Carbonylative difunctionalization of alkenes, which installs a unique functional group and a carbonyl group across the C−C double bonds, offers a high potential strategy for the selective synthesis of β‐substituted carbonyl compounds. The carbonylative difunctionalization of alkenes involves the formation of three σ‐bonds and two stereocenters as well as a carbonyl group in a single transformation. Careful design of the substrate and control of reaction pathway would result unexpected advantages in constructing complex structures, which are ubiquitous in natural products, pharmaceuticals and functional materials. In this Review, the important advances and contributions in carbonylative difunctionalization of alkenes are summarized based on the different reaction types, with the wish to inspire future studies and promote further developments in this field.

中文翻译：

---

烯烃羰基化双官能化的最新进展

羰基化反应是快速建立羰基结构的最有力方法之一，已广泛应用于学术和工业领域。烯烃的羰基化双官能化在C-C双键上安装了独特的官能团和羰基，为选择性合成β-取代的羰基化合物提供了高潜力的策略。烯烃的羰基双官能化涉及形成三个σ一次转换即可键合和两个立体中心以及一个羰基。仔细设计底物并控制反应路径会在构建复杂结构中产生意想不到的优势，而这些复杂结构在天然产物，药物和功能材料中无处不在。在本综述中，基于不同的反应类型总结了烯烃羰基双官能化的重要进展和贡献，以期启发未来的研究并促进该领域的进一步发展。