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A comprehensive review of the polymer‐based hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications
Polymer Engineering and Science ( IF 3.2 ) Pub Date : 2020-06-22 , DOI: 10.1002/pen.25410 Katarina Nešović 1 , Vesna Mišković‐Stanković 1
Polymer Engineering and Science ( IF 3.2 ) Pub Date : 2020-06-22 , DOI: 10.1002/pen.25410 Katarina Nešović 1 , Vesna Mišković‐Stanković 1
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Modernization and improvement of wound dressing materials is an important topic in biomaterials and biomedicine fields, as the traditional materials are inadequate and susceptible to bacterial infections. In recent times, polymer‐based hydrogel materials have presented themselves as excellent candidates for new‐generation wound dressings with improved properties, such as high sorption ability, good mechanical properties, and low adhesiveness. Additionally, cross linked hydrogel matrices serve as excellent carriers for controlled release of antibacterial agents, such as silver nanoparticles (AgNPs), which are preferred over conventional antibiotics due to multi‐phase mechanism of action and low susceptibility to induce bacterial resistance. Their incorporation inside polymer matrices allows improvement of wound dressing properties and sustained protection against bacterial infection. Electrochemical methods for AgNPs synthesis are facile and green alternatives to chemical routes, allowing the formation of highly stable AgNPs with strong antibacterial effect. In this article, we aim to provide a comprehensive review of the existing research on the topic of electrochemically synthesized silver nanoparticles incorporated in polymer matrices with a special focus on the chitosan‐based hydrogels as prospective materials for wound dressing applications.
中文翻译：
聚合物基水凝胶与电化学合成银纳米颗粒的综合综述，用于伤口敷料应用
伤口敷料的现代化和改进是生物材料和生物医学领域的重要课题，因为传统材料不足且易受细菌感染。近年来，基于聚合物的水凝胶材料已成为新一代伤口敷料的优秀候选者，它们具有改善的特性，例如高吸附能力，良好的机械性能和低粘附性。此外，交联的水凝胶基质还可以作为控释抗菌剂的极佳载体，例如银纳米颗粒（AgNPs），由于其多相作用机制和较低的诱导细菌耐药性的敏感性，因此优于常规抗生素。将它们掺入聚合物基质中可以改善伤口敷料的性能，并持续保护细菌免受感染。AgNPs合成的电化学方法是化学路线的便捷和绿色替代品，可形成具有强大抗菌作用的高度稳定的AgNPs。在本文中，我们旨在全面综述与聚合物基质中电化学合成的银纳米颗粒有关的现有研究，特别关注基于壳聚糖的水凝胶作为伤口敷料应用的潜在材料。
更新日期：2020-06-22
中文翻译：
聚合物基水凝胶与电化学合成银纳米颗粒的综合综述，用于伤口敷料应用
伤口敷料的现代化和改进是生物材料和生物医学领域的重要课题，因为传统材料不足且易受细菌感染。近年来，基于聚合物的水凝胶材料已成为新一代伤口敷料的优秀候选者，它们具有改善的特性，例如高吸附能力，良好的机械性能和低粘附性。此外，交联的水凝胶基质还可以作为控释抗菌剂的极佳载体，例如银纳米颗粒（AgNPs），由于其多相作用机制和较低的诱导细菌耐药性的敏感性，因此优于常规抗生素。将它们掺入聚合物基质中可以改善伤口敷料的性能，并持续保护细菌免受感染。AgNPs合成的电化学方法是化学路线的便捷和绿色替代品，可形成具有强大抗菌作用的高度稳定的AgNPs。在本文中，我们旨在全面综述与聚合物基质中电化学合成的银纳米颗粒有关的现有研究，特别关注基于壳聚糖的水凝胶作为伤口敷料应用的潜在材料。
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