Heating/Solvent Responsive Shape-Memory Polymers for Implant Biomedical Devices in Minimally Invasive Surgery: Current Status and Challenge.,Macromolecular Bioscience

当前位置： X-MOL 学术 › Macromol. Biosci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Heating/Solvent Responsive Shape-Memory Polymers for Implant Biomedical Devices in Minimally Invasive Surgery: Current Status and Challenge.
Macromolecular Bioscience ( IF 4.4 ) Pub Date : 2020-06-22 , DOI: 10.1002/mabi.202000108
Rui Xiao ₁ , Wei Min Huang ₂

Affiliation

This review is about the fundamentals and practical issues in applying both heating and solvent responsive shape memory polymers (SMPs) for implant biomedical devices via minimally invasive surgery. After revealing the general requirements in the design of biomedical devices based on SMPs and the fundamentals for the shape‐memory effect in SMPs, the underlying mechanisms, characterization methods, and several representative biomedical applications, including vascular stents, tissue scaffolds, occlusion devices, drug delivery systems, and the current R&D status of them, are discussed. The new opportunities arising from emerging technologies, such as 3D printing, and new materials, such as vitrimer, are also highlighted. Finally, the major challenge that limits the practical clinical applications of SMPs at present is addressed.

中文翻译：

用于微创手术中的植入式生物医学设备的加热/溶剂响应型形状记忆聚合物：现状和挑战。

这篇评论是关于通过微创手术将加热和溶剂响应形状记忆聚合物（SMP）应用于植入式生物医学设备的基本原理和实际问题。在揭示了基于SMP的生物医学设备设计的一般要求以及SMP的形状记忆效应的基本原理，潜在的机理，表征方法以及几种代表性的生物医学应用后，包括血管支架，组织支架，阻塞设备，药物讨论了交付系统及其当前的研发状态。还着重指出了新兴技术（例如3D打印）和新材料（例如玻璃陶瓷）带来的新机遇。最后，解决了目前限制SMP实际临床应用的主要挑战。

更新日期：2020-06-22

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11