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Fast effectiveness of a solubilized low-dose budesonide nasal spray in allergic rhinitis
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2020-07-07 , DOI: 10.1111/cea.13691
Petra Zieglmayer 1, 2 , René Schmutz 1, 3 , Patrick Lemell 1 , Nicole Unger-Manhart 4 , Sabine Nakowitsch 4 , Andreas Goessl 4 , Markus Savli 5 , René Zieglmayer 1 , Eva Prieschl-Grassauer 4
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Budesonide, a poorly water‐soluble corticosteroid, is currently marketed as a suspension. Budesolv is a novel aqueous formulation containing dissolved budesonide showing increased local availability in preclinical models. Budesolv contains ~85% less corticosteroid than the marketed comparator.

中文翻译:

溶解性低剂量布地奈德鼻喷雾剂在过敏性鼻炎中的快速疗效

布地奈德是一种水溶性差的皮质类固醇,目前以混悬液形式销售。Budesolv 是一种含有溶解布地奈德的新型水性制剂,在临床前模型中显示出增加的局部可用性。Budesolv 所含的皮质类固醇比市售的比较剂少约 85%。
更新日期:2020-07-07
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