Metamizole belongs to the group of non-opioid analgesics and, as for other non-steroidal anti-inflammatory drugs (NSAID) such as acetylsalicylic acid, diclofenac or ibuprofen, both isoforms of cyclooxygenase are inhibited. Metamizole is an important trigger of non-allergic and allergic hypersensitivity reactions and has been withdrawn from the US, Australian, and UK market due to the risk of agranulocytosis, but is still available and broadly used in many countries of Europe, Central and South America, and Asia.

中文翻译：

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安乃近引起的反应作为药物超敏反应的范式：非过敏反应、过敏反应和迟发型过敏反应

安乃近属于非阿片类镇痛药，至于其他非甾体抗炎药 (NSAID)，如乙酰水杨酸、双氯芬酸或布洛芬，环加氧酶的两种亚型均受到抑制。安乃近是非过敏性和过敏性超敏反应的重要触发因素，因存在粒细胞缺乏症风险已从美国、澳大利亚和英国市场撤出，但在欧洲、中美洲和南美洲的许多国家仍然可用并广泛使用，和亚洲。