Monitoring the trace amount of chemicals in various samples remains a challenge. This study was conducted to develop a new solid‐phase microextraction (SPME) system (inside‐tube SPME) for trace analysis of n‐hexane in air and urine matrix. The inside‐tube SPME system was prepared based on the phase separation technique. A mixture of carbon aerogel and polystyrene was loaded inside the needle using methanol as the anti‐solvent. The air matrix of n‐hexane was prepared in a Tedlar bag, and n‐hexane vapor was sampled at a flow rate of 0.1 L/min. Urine samples spiked with n‐hexane were used to simulate the sampling method. The limit of detection using the inside‐tube SPME was 0.0003 μg/sample with 2.5 mg of adsorbent, whereas that using the packed needle was 0.004 μg/sample with 5 mg of carbon aerogel. For n‐hexane analysis, the day‐to‐day and within‐day coefficient variation were lower than 1.37%, with recoveries over 98.41% achieved. The inside‐tube SPME is an inter‐link device between two sample preparation methods, namely, a needle trap device and an SPME system. The result of this study suggested the use of the inside‐tube SPME containing carbon aerogel (adsorbent) as a simple and fast method with low cost for n‐hexane evaluation.

中文翻译：

---

管内固相微萃取作为固相微萃取和针头装置之间的链接，用于空气和尿液顶空中的正己烷评估。

监测各种样品中痕量化学物质仍然是一个挑战。进行该研究以开发用于痕量分析的新的固相微萃取（SPME）系统（内管SPME）ñ在空气中和尿矩阵正己烷。管内SPME系统是基于相分离技术制备的。使用甲醇作为抗溶剂，将碳气凝胶和聚苯乙烯的混合物装入针头内。的空气矩阵ñ -己烷在泰德拉集气袋制备，并且Ñ己烷蒸气以0.1L / min的流速进行取样。尿样中掺有n用正己烷模拟采样方法。使用内管SPME的检测限为0.0003μg/样品，含2.5 mg吸附剂，而使用填充针的检测限为0.004μg/样品，含5 mg碳气凝胶。对于Ñ己烷分析，天到一天和日内变异系数分别为低于1.37％，超过98.41％的回收率来实现。内管SPME是两种样品制备方法之间的相互连接的装置，即针头捕集装置和SPME系统。本研究的结果表明了使用含有碳气凝胶（吸附剂）作为一个简单的和快速的方法以低成本为内管SPME的Ñ正己烷评价。