Fourteen new meroterpenoid compounds, corypsoriols A–N (1–14), and eight known ones (15–22), were isolated from the fruits of Psoralea corylifolia. The absolute configurations of these new compounds were confirmed by NOESY spectrum, ECD calculation, and single crystal X-ray diffraction. Corypsoriols A and B were a novel skeleton which possessed a 6/5/6 tricyclic system, and their plausible biosynthetic pathway was proposed. The cytotoxicity of uncyclized meroterpenoids were stronger than those of cyclized ones, and the half maximal inhibitory concentration values of bakuchiol (15) against NCI–N87, HepG2, HCT-116, Hela and B16–F10 cell lines were in the range of 5–20 μM.

从补骨脂（Psoralea corylifolia）的果实中分离出了十四种新的金属萜类化合物，花椰油酚A–N（1 – 14）和八种已知的（15 – 22）。这些新化合物的绝对构型已通过NOESY光谱，ECD计算和单晶X射线衍射证实。二十碳五烯酚A和B是具有6/5/6三环系统的新型骨架，并提出了它们可能的生物合成途径。未环化的类胡萝卜素的细胞毒性要强于环化的类胡萝卜素，并且爆裂酚（15）对NCI-N87，HepG2，HCT-116，Hela和B16-F10细胞系的半数最大抑制浓度值在5– 20  μM.