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Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses.
Research in Veterinary Science ( IF 2.4 ) Pub Date : 2020-06-20 , DOI: 10.1016/j.rvsc.2020.06.017
Juliana de Moura Alonso 1 , Carolina Soares Esper 1 , José Carlos Figueiredo Pantoja 2 , Gustavo Dos Santos Rosa 1 , Rodrigo Rosa Giampietro 3 , Bruna Dos Santos 4 , Simony Trevizan Guerra 2 , Márcio Garcia Ribeiro 2 , Regina Kiomi Takahira 4 , Marcos Jun Watanabe 1 , Ana Liz Garcia Alves 1 , Celso Antônio Rodrigues 1 , Henry David Mogollón García 1 , Carlos Alberto Hussni 1
Affiliation  

Difference in blood and peritoneal glucose (DBPG) is used in clinical practice to support a diagnosis of septic peritonitis in horses. It is inexpensive, easy and rapid to perform. The aim of this study was to evaluate the accuracy of the DBPG to differentiate between septic and non-septic peritonitis in horses. Blood and peritoneal fluids were harvested from suspected animals. Plasma and peritoneal glucose levels, total nucleated cell count, direct microscopic and microbiological examinations of the peritoneal fluid were evaluated. Using DBPG levels, the animals were classified into two groups: difference ≥ 50 mg/dL (positive test) and difference < 50 mg/dL (negative test). Positive microbiological examination and/or presence of bacteria in direct microscopic examination was used as a gold standard to detect septic peritonitis. The accuracy parameters analysed were: sensitivity, specificity, and positive/negative predictive values, for which the results were respectively: 0.23, 0.91, 0.60 and 0.67. Due to poor accuracy, other cut-off margins and peritoneal glucose concentrations were evaluated. The test was considered most accurate when the DBPG was zero with sensitivity, specificity, and positive/negative predictive values of 0.85, 0.82, 0.73, 0.90 respectively. Peritoneal glucose concentrations alone were not a reliable feature to detect peritonitis. DBPG ≥50 mg/dL, widely used for the diagnosis of septic peritonitis, does not have a good accuracy and the DBPG = 0 has a better accuracy for detecting the disease.



中文翻译:

区分血液和腹膜葡萄糖的准确性,以区分马的败血性和非败血症性腹膜炎。

血液和腹膜葡萄糖(DBPG)的差异在临床实践中用于支持对马的败血性腹膜炎的诊断。它便宜,易于执行且快速。这项研究的目的是评估DBPG区分马的败血性和非败血症性腹膜炎的准确性。从可疑动物中采集血液和腹膜液。评估血浆和腹膜葡萄糖水平,总有核细胞数,腹膜液直接显微镜和微生物学检查。使用DBPG水平,将动物分为两组:差异≥50 mg / dL(阳性试验)和差异≤50 mg / dL(阴性试验)。阳性微生物检查和/或直接显微镜检查中细菌的存在被用作检测败血症性腹膜炎的金标准。分析的准确性参数为:敏感性,特异性和阳性/阴性预测值,其结果分别为:0.23、0.91、0.60和0.67。由于准确性差,因此评估了其他临界值和腹膜葡萄糖浓度。当DBPG为零时,灵敏度,特异性和阳性/阴性预测值分别为0.85、0.82、0.73和0.90,该测试被认为是最准确的。单独的腹膜葡萄糖浓度不是检测腹膜炎的可靠特征。DBPG≥50mg / dL,广泛用于败血性腹膜炎的诊断,其准确性不高,DBPG = 0对疾病的检测准确性更高。由于准确性差,因此评估了其他临界值和腹膜葡萄糖浓度。当DBPG为零时,灵敏度,特异性和阳性/阴性预测值分别为0.85、0.82、0.73和0.90,该测试被认为是最准确的。单独的腹膜葡萄糖浓度不是检测腹膜炎的可靠特征。DBPG≥50mg / dL,广泛用于败血性腹膜炎的诊断,其准确性不高,DBPG = 0对疾病的检测准确性更高。由于准确性差,因此评估了其他临界值和腹膜葡萄糖浓度。当DBPG为零时,灵敏度,特异性和阳性/阴性预测值分别为0.85、0.82、0.73和0.90,该测试被认为是最准确的。单独的腹膜葡萄糖浓度不是检测腹膜炎的可靠特征。DBPG≥50mg / dL,广泛用于败血性腹膜炎的诊断,其准确性不高,DBPG = 0对疾病的检测准确性更高。单独的腹膜葡萄糖浓度不是检测腹膜炎的可靠特征。DBPG≥50mg / dL,广泛用于败血性腹膜炎的诊断,其准确性不高,DBPG = 0对疾病的检测准确性更高。单独的腹膜葡萄糖浓度不是检测腹膜炎的可靠特征。DBPG≥50mg / dL,广泛用于败血性腹膜炎的诊断,其准确性不高,DBPG = 0对疾病的检测准确性更高。

更新日期:2020-07-05
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