Araçá fruits (Psidium cattleianum Sabine) have been reported to have several biological activities, including the inhibition of the digestives enzymes. Nevertheless, the compounds responsible for these activities are not known. This study evaluated the potential of araçá phenolic fractions to inhibit the activity of α-glucosidase and α-amylase and related it to their phenolic composition. Extracts of edible portions (pulp-peel and seeds) of fruits from three araçá genotypes were purified and fractionated. Total phenolic content was determined using a spectrophotometric method, and individual phenolic compounds were quantified using HPLC-MS. Their enzyme inhibition and antioxidant potential were measured using in vitro assays. Higher amounts of total phenolic content were observed in pulp-peel than in seeds. These results were partially associated with the slightly higher enzyme inhibition of pulp-peel fractions. In general, araçá phenolic fractions were more active towards α-glucosidase than α-amylase when compared to acarbose, the current drug used to inhibit α-glucosidases. The antioxidant potential was dependent on accession, part of the fruit and fraction. Moreover, compounds present in the crude and purified extracts, and fractions III (quercetin, ellagic acid and p-coumaric acid) and IV (cyanidin-3-O-glucoside and malvidin-3-O-glucoside) for some samples resulted in significant inhibition of the two enzymes.

据报道，Araçá水果（Psidium cowianum Sabine）具有多种生物学活性，包括抑制消化酶。然而，尚不清楚负责这些活性的化合物。这项研究评估了花生酚类馏分抑制α-葡萄糖苷酶和α-淀粉酶活性的潜力，并将其与其酚类成分相关联。纯化并分馏了三种阿拉伯基因型水果的可食用部分（果皮和种子）的提取物。使用分光光度法确定总酚含量，并使用HPLC-MS对单个酚化合物进行定量。使用体外方法测定了它们的酶抑制作用和抗氧化能力分析。果皮中的总酚含量高于种子中的总酚含量。这些结果部分与纸浆果皮部分的酶抑制作用稍高有关。通常，与目前用于抑制α-葡萄糖苷酶的阿卡波糖相比，阿拉伯酚组分对α-葡萄糖苷酶的活性比α-淀粉酶高。抗氧化剂的潜力取决于果实，部分水果和分数。此外，粗制和纯化提取物中存在的化合物以及某些样品的馏分III（槲皮素，鞣花酸和对香豆酸）和IV（花青素-3- O-葡萄糖苷和麦维京-3 - O-葡萄糖苷）导致显着抑制两种酶。