Hexachlorophene (HCP) is used in a range of general cleaning and disinfecting products and has received increased attention due to its damaging effect to the central nervous system in animals and its toxicity in humans. The chemical oxidation of HCP by KMnO₄ was performed to systematically evaluate the effects of oxidant dose, pH, temperature, typical anions, humic acid (HA), and various matrices on HCP removal. The second-order rate constant for HCP was determined to be 4.83 × 10⁴ M⁻¹ s⁻¹ at pH 7.0 and 25 °C. The presence of HA can inhibit the removal of HCP by KMnO₄, while Cl⁻, NO₃⁻, SO₄²⁻, PO₄³⁻, and CO₃²⁻ have negligible effects. Degradation products analysis of the reaction, as well as theoretical calculations of HCP molecule and its phenoxy radical species, indicated that KMnO₄ oxidation for HCP included a C–C bridge bond cleavage, hydroxylation, direct oxidation and self-coupling, and cross-coupling reactions. This study revealed that KMnO₄ oxidation is an effective technique for eliminating HCP in real water and wastewater.

六氯苯（HCP）用于多种常规清洁和消毒产品，由于其对动物中枢神经系统的破坏作用及其对人的毒性，因此受到越来越多的关注。通过KMnO ₄对HCP进行化学氧化，以系统地评估氧化剂剂量，pH，温度，典型阴离子，腐殖酸（HA）和各种基质对HCP去除的影响。在pH 7.0和25°C下，HCP的二级速率常数确定为4.83×10 ⁴  M ^-1  s ^-1。HA的存在可通过高锰酸钾抑制去除HCP的₄，而氯^-，NO ₃ ^-，SO ₄ ^2-，PO₄ ³⁻和CO ₃ ^2-的影响可忽略不计。反应的降解产物分析以及HCP分子及其苯氧基自由基的理论计算表明，HCP的KMnO ₄氧化包括C–C桥键断裂，羟基化，直接氧化和自偶联和交叉偶联。反应。这项研究表明，KMnO ₄氧化是消除实际水和废水中HCP的有效技术。