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Synthesis of Phosphinic Analogue of Alanylleucine
Russian Journal of General Chemistry ( IF 0.9 ) Pub Date : 2020-06-20 , DOI: 10.1134/s1070363220040313
S. R. Golovash , O. S. Grigorkevich , G. S. Tsebrikova , M. E. Dmitriev , V. V. Ragulin

Abstract

The amidoalkylation reactions of a phosphonous acid containing a structural isostere of leucine in acetyl chloride and(or) acetic anhydride were studied under conditions of acid catalysis. A two-component method for the synthesis of a phosphinic analogue of alanylleucine using ethylidenebis(benzylcarbamate) was proposed.


中文翻译:

丙氨酰亮氨酸的膦酸酯类似物的合成

摘要

在酸催化条件下,研究了含有亮氨酸结构等位异构体的亚磷酸在乙酰氯和(或)乙酸酐中的酰胺烷基化反应。提出了使用亚乙基双(苄基氨基甲酸酯)合成丙氨酰亮氨酸的次膦酸酯类似物的两组分方法。
更新日期:2020-06-20
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