Abstract

The reaction of carboxylic acid amides with malonyl chloride in acetonitrile or tetrahydrofuran without heating leads to the formation of previously unknown 2-substituted 5-hydroxypyrano[2,3-d][1,3]oxazines. The structure of the obtained compounds was established by high resolution mass spectrometry, NMR spectroscopy, and X-ray analysis.

中文翻译：

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新型2-取代的5-羟基吡喃并[2,3-d] [1,3]恶嗪-4,7-二酮的合成

摘要

在不加热的情况下，羧酸酰胺与丙二酰氯在乙腈或四氢呋喃中的反应导致形成以前未知的2-取代的5-羟基吡喃并[2,3- d ] [1,3]恶嗪。通过高分辨率质谱，NMR光谱和X射线分析来确定获得的化合物的结构。