Appropriate scaffolds for tissue-engineered bone not only require mechanical strength, but also conditions that promote new bone growth. Bone tissue engineering scaffolds should establish the internal pore structure of the scaffolds and promote new bone growth. Additive manufacturing technology is widely used in the field of bone tissue engineering because it can directly and accurately construct the pore structure in 3D space, ensure internal connectivity of the scaffolds, and directly use biological materials. This paper reviews the development of additive manufacturing technology for bone tissue engineering. The differences between various additive manufacturing technologies are reviewed, with emphasis on the application of new technologies and materials. This paper also reviews the modeling processes used in bone tissue engineering, with emphasis on the optimization of the architectural design to achieve gradient structure and improved porosity and mechanical properties. Finally, this paper summarizes the 3D bioprinting technology that has fluid containing nutrients, matrix, and cells as constituent materials. Current problems and directions for the future development of additive manufacturing technology in the field of bone tissue engineering are also discussed.

用于组织工程骨骼的合适支架不仅需要机械强度，而且还需要促进新骨骼生长的条件。骨组织工程支架应建立支架的内部孔结构并促进新的骨骼生长。增材制造技术可以直接，准确地在3D空间中构造孔结构，确保支架的内部连通性并直接使用生物材料，因此在骨组织工程领域得到了广泛的应用。本文回顾了骨组织工程增材制造技术的发展。综述了各种增材制造技术之间的差异，重点是新技术和新材料的应用。本文还回顾了骨组织工程中使用的建模过程，重点在于优化建筑设计以实现渐变结构以及改善的孔隙率和机械性能。最后，本文总结了以含有营养素，基质和细胞的液体为构成材料的3D生物打印技术。还讨论了骨组织工程领域增材制造技术的当前问题和未来发展方向。