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Examining Correlates of Pre-ART and Early ART Adherence to Identify Key Factors Influencing Adherence Readiness.
AIDS and Behavior ( IF 2.7 ) Pub Date : 2020-06-22 , DOI: 10.1007/s10461-020-02947-6
Kyle Gordon 1 , Risa M Hoffman 1 , Gulrez Azhar 2 , Daniel Ramirez 3 , Stefan Schneider 3 , Glenn J Wagner 2
Affiliation  

Although current standard of care for HIV typically involves immediate initiation of antiretroviral therapy (ART), most patients can benefit from first assessing adherence readiness and addressing any barriers to optimal adherence. A sample of 176 HIV patients planning to start ART enrolled in a controlled trial of an adherence intervention that was based on the Information Motivation and Behavioral skills (IMB) model of health behavior. We examined correlates of multiple adherence readiness measures, as well as electronically measured early ART adherence, to identify variables most important for readiness to adhere well at the start of treatment. Education level, recency of HIV diagnosis and knowledge and commitment to adherence were found to be associated with both ART readiness and early ART adherence. These findings suggest that resources to support adherence readiness should target more experienced HIV patients, and strive to bolster knowledge and attitudes that reinforce commitment to adherence.



中文翻译:

检查 ART 前和早期 ART 依从性的相关性,以确定影响依从性准备情况的关键因素。

尽管当前的 HIV 护理标准通常涉及立即开始抗逆转录病毒疗法 (ART),但大多数患者可以从首先评估依从性准备情况和解决最佳依从性的任何障碍中受益。计划开始 ART 的 176 名 HIV 患者样本参加了一项依从性干预的对照试验,该试验基于健康行为的信息动机和行为技能 (IMB) 模型。我们检查了多种依从性准备措施的相关性,以及电子测量的早期 ART 依从性,以确定在治疗开始时对良好依从性的准备最重要的变量。发现教育水平、HIV 诊断的新近程度和知识以及对依从性的承诺与 ART 准备情况和早期 ART 依从性有关。

更新日期:2020-06-22
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