The emergence and expansion of antibiotic resistance makes it necessary to have alternative anti-infective agents, among which silver nanoparticles (AgNPs) display especially interesting properties. AgNPs carry out their antibacterial action through various molecular mechanisms, and the magnitude of the observed effect is dependent on multiple, not fully understood, aspects, particle shape being one of the most important. In this article, we conduct a study of the antibacterial effect of a recently described type of AgNP: silver nanorings (AgNRs), making comparisons with other alternative types of AgNP synthesized in parallel using the same methodology. When they act on planktonic forms, AgNRs produce a smaller effect on the viability of different bacteria than nanoparticles with other structures although their effect on growth is more intense over a longer period. When their action on biofilms is analyzed, AgNRs show a greater concentration-dependent effect. In both cases it was observed that the effect on inhibition depends on the microbial species, but not its Gram positive or negative nature. Growth patterns in silver-resistant Salmonella strains suggest that AgNRs work through different mechanisms to other AgNPs. The antibacterial effect is also produced to some extent by the conditioning of culture media or water by contact with AgNPs but, at least over short periods of time, this is not due to the release of Ag ions. AgNRs constitute a new type of AgNP, whose antibacterial properties depend on their shape, and is capable of acting efficiently on both planktonic bacteria and biofilms.

中文翻译：

---

银纳米环的抗菌作用。

抗生素抗性的出现和扩展使得必须具有替代的抗感染剂，其中银纳米颗粒（AgNPs）表现出特别令人感兴趣的特性。AgNPs通过各种分子机制执行其抗菌作用，并且观察到的效果的大小取决于多个尚未完全理解的方面，颗粒形状是最重要的方面之一。在本文中，我们对最近描述的AgNP类型：银纳米环（AgNRs）的抗菌效果进行了研究，并与使用相同方法并行合成的其他替代AgNP类型进行了比较。当它们作用于浮游形式时，与具有其他结构的纳米粒子相比，AgNRs对不同细菌的生存力影响较小，尽管它们在较长时期内对生长的影响更大。当分析它们对生物膜的作用时，AgNRs显示出更大的浓度依赖性效应。在这两种情况下，均观察到抑制效果取决于微生物种类，而不取决于其革兰氏阳性或阴性性质。抗银沙门氏菌菌株的生长模式表明，AgNRs通过与其他AgNPs不同的机制起作用。通过与AgNPs接触来调节培养基或水也可以在某种程度上产生抗菌作用，但是至少在短时间内，这不是由于Ag离子的释放。AgNRs构成一种新型的AgNP，其抗菌性能取决于其形状，