Red blood cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) have shown a prognostic value in various clinical settings. We aimed to investigate the association between RDW, NLR, and in-hospital mortality in patients with dyspnea. In this retrospective study with the Medical Information Mart for Intensive Care III database (version 1.4), adult patients who came to the emergency department with dyspnea were included. Patients’ comorbidities, hematological parameters within the first 48 hours after admission to the emergency department, and in-hospital mortality were extracted. The relationships between RDW, NLR, and in-hospital mortality were analyzed with the receiver operating characteristic (ROC) curve analysis and multivariate logistic regression model. We found that hospital survivors had significantly lower NLR than those who died. However, RDW was not significantly increased in patients who died during the hospitalization. The area under the ROC curve of NLR for predicting in-hospital mortality was 0.62. On multivariate analysis, NLR was not independently associated with in-hospital mortality. On further analysis, lymphocyte percentage was independently associated with in-hospital mortality, with an odds ratio of 0.56. Therefore, we concluded that RDW and NLR are not reliable parameters to predict in-hospital mortality in critically ill patients admitted to the emergency department with dyspnea.

中文翻译：

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入急诊室的呼吸困难患者的红细胞分布宽度，中性粒细胞与淋巴细胞之比和住院死亡率。

红细胞分布宽度（RDW）和中性白细胞与淋巴细胞之比（NLR）在各种临床情况下均显示出预后价值。我们旨在调查呼吸困难患者的RDW，NLR和住院死亡率之间的关系。在这项针对重症监护医学信息数据库III（1.4版）的回顾性研究中，纳入了急诊呼吸困难的成年患者。提取患者的合并症，入院急诊室后48小时内的血液学参数以及住院死亡率。通过受试者工作特征（ROC）曲线分析和多元logistic回归模型分析了RDW，NLR和住院死亡率之间的关系。我们发现，医院幸存者的NLR明显低于死者。但是，住院期间死亡的患者的RDW并未显着增加。NLR的ROC曲线下预测医院内死亡率的面积为0.62。在多变量分析中，NLR与住院死亡率没有独立相关。在进一步分析中，淋巴细胞百分比与院内死亡率独立相关，比值比为0.56。因此，我们得出的结论是，RDW和NLR不是可靠的参数来预测急诊呼吸困难的重症患者的院内死亡率。在多变量分析中，NLR与住院死亡率没有独立相关。在进一步分析中，淋巴细胞百分比与院内死亡率独立相关，比值比为0.56。因此，我们得出的结论是，RDW和NLR不是可靠的参数来预测急诊呼吸困难的重症患者的院内死亡率。在多变量分析中，NLR与住院死亡率没有独立相关。在进一步分析中，淋巴细胞百分比与院内死亡率独立相关，比值比为0.56。因此，我们得出的结论是，RDW和NLR不是可靠的参数来预测急诊呼吸困难的重症患者的院内死亡率。