Efficacy of single and multiple oral doses of fosfomycin against Pseudomonas aeruginosa urinary tract infections in a dynamic in vitro bladder infection model,Journal of Antimicrobial Chemotherapy

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Efficacy of single and multiple oral doses of fosfomycin against Pseudomonas aeruginosa urinary tract infections in a dynamic in vitro bladder infection model
Journal of Antimicrobial Chemotherapy ( IF 3.9 ) Pub Date : 2020-05-03 , DOI: 10.1093/jac/dkaa127
Iain J Abbott _{1,

2} , Elke van Gorp ₂ , Rixt A Wijma _{2,

3} , Jordy Dekker ₂ , Peter D Croughs ₂ , Joseph Meletiadis ₄ , Johan W Mouton ₂ , Anton Y Peleg _{1,

5}

Affiliation

We used a dynamic bladder infection in vitro model with synthetic human urine (SHU) to examine fosfomycin exposures to effectively kill, or prevent emergence of resistance, among Pseudomonas aeruginosa isolates.

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