当前位置:
X-MOL 学术
›
J. Antimicrob. Chemother.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Inhaled tigecycline is effective against Mycobacterium abscessus in vitro and in vivo
Journal of Antimicrobial Chemotherapy ( IF 3.9 ) Pub Date : 2020-04-15 , DOI: 10.1093/jac/dkaa110 Camron Pearce 1 , Mike M Ruth 2 , Lian J Pennings 2 , Heiman F L Wertheim 2 , Amanda Walz 1 , Wouter Hoefsloot 3 , Carolien Ruesen 2 , Juan Muñoz Gutiérrez 1 , Mercedes Gonzalez-Juarrero 1 , Jakko van Ingen 2
Journal of Antimicrobial Chemotherapy ( IF 3.9 ) Pub Date : 2020-04-15 , DOI: 10.1093/jac/dkaa110 Camron Pearce 1 , Mike M Ruth 2 , Lian J Pennings 2 , Heiman F L Wertheim 2 , Amanda Walz 1 , Wouter Hoefsloot 3 , Carolien Ruesen 2 , Juan Muñoz Gutiérrez 1 , Mercedes Gonzalez-Juarrero 1 , Jakko van Ingen 2
Affiliation
Mycobacterium abscessus causes chronic pulmonary infections. Owing to its resistance to most classes of antibiotics, treatment is complex and cure rates are only 45%. Tigecycline is active against M. abscessus, but severe toxicity and the need for IV administration limit its use.
中文翻译:
吸入替加环素在体外和体内均可有效治疗脓肿分枝杆菌
脓肿分枝杆菌会引起慢性肺部感染。由于其对大多数抗生素的抗药性,因此治疗非常复杂,治愈率仅为45%。替加环素对脓肿支原体具有活性,但严重的毒性和静脉内给药的需求限制了其使用。
更新日期:2020-06-19
中文翻译:
吸入替加环素在体外和体内均可有效治疗脓肿分枝杆菌
脓肿分枝杆菌会引起慢性肺部感染。由于其对大多数抗生素的抗药性,因此治疗非常复杂,治愈率仅为45%。替加环素对脓肿支原体具有活性,但严重的毒性和静脉内给药的需求限制了其使用。