Motion is problematic during radiotherapy as it could lead to potential underdosage of the tumor, and/or overdosage in organs-at-risk. A solution is adaptive radiotherapy guided by magnetic resonance imaging (MRI). MRI allows for imaging of target volumes and organs-at-risk before and during treatment delivery with superb soft tissue contrast in any desired orientation, enabling motion management by means of (real-time) adaptive radiotherapy. The noise navigator, which is independent of the MR signal, could serve as a secondary motion detection method in synergy with MR imaging. The feasibility of respiratory motion detection by means of the noise navigator was demonstrated previously. Furthermore, from electromagnetic simulations we know that the noise navigator is sensitive to tissue displacement and thus could in principle be used for the detection of various types of motion. In this study we demonstrate the detection of various types of motion for three anatomi...

中文翻译：

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用于MRI引导放射治疗的噪声导航仪：一种检测生理运动的独立方法

运动在放疗期间存在问题，因为它可能导致肿瘤的潜在剂量不足和/或高风险器官的剂量过多。一种解决方案是在磁共振成像（MRI）的指导下进行自适应放射治疗。MRI允许在治疗前和治疗过程中对靶区和处于危险状态的器官进行成像，并以任何期望的方向提供出色的软组织对比度，从而可以通过（实时）自适应放射疗法进行运动管理。噪声导航器与MR信号无关，可以用作与MR成像协同作用的辅助运动检测方法。先前已经证明了通过噪声导航仪检测呼吸运动的可行性。此外，从电磁仿真中我们知道，噪声导航器对组织位移很敏感，因此原则上可以用于检测各种类型的运动。在这项研究中，我们演示了对三种解剖结构的各种类型运动的检测。